Looking for cheap flights from Columbia to Chicago O'Hare? FareFort™ helps you compare real-time fares across top airlines and booking sites. Live prices for 2025-12-10 → 2025-12-17 are displayed below.
The Columbia–Chicago O'Hare route connects two major travel hubs. Average flight time is approximately Varies by route, with several daily nonstop and connecting options. Major airlines include Multiple airlines.